The platform, which is accessed via user workspaces, will enable discovery of local and federated cohorts and datasets and provide seamless access to a suite of tools and workflows that enable reproducible data analysis and cross-consortium projects. These will be interfaced with a choice of computing infrastructures that are feasible for African scientists, including public and private Cloud and local HPC facilities and, where necessary, protected through authorization and authentication access protocols. The first implementations of eLwazi use Terra (https://elwazi.terra.bio/), which accesses Google Cloud and Gen3, which uses Amazon Web Services.